Benzocaine also known as aminobenzoate ethyl ester, sinecetine.The precipitates from water are colorless or white rhombic needle-like crystals or crystalline powder, and the precipitates from ether are square crystals.Odorless.Has a bitter taste.Relative sub-chemicalbook mass .Melting point is 92 ºC.Boiling point 310ºC, 183 ~ 184ºC().Insoluble in water, soluble in ethanol, ether and chloroform, but also soluble in almond oil, olive oil and dilute acids.Stable in the air.Taking p-nitrotoluene as raw material, in sulfuric acid, with sodium dichromate oxidation, p-nitrobenzoic acid, ethanol esterification reaction, separation, p-nitrobenzoic acid ethyl ester in acetic acid solution, iron powder at 85 ~ 95ºC reduction, benzocaine crude product.After separation, washing with water, and then recrystallization in ethanol refining.
