Betadex Sulfobutyl Ether Sodium Salt CAS No.: 182410-00-0
Description:
Zhiyuan Betadex Sulfobutyl Ether Sodium Salt is an anionic bcyclodextrin derivative with a sodium sulfonate salt separated from the hydrophobic cavity by a butyl spacer group. The substituent is introduced at positions 2, 3, and 6 in at least one of the glucopyranose units in the cyclodextrin structure. Introducing the sulfobutylether (SBE) into beta cyclodextrin can produce materials with different degrees of substitution, theoretically from 1 to 21; the hepta-substituted preparation (SBE7-b-CD) is the cyclodextrin with the most desirable drug carrier properties. Betadex Sulfobutyl Ether Sodium Salt China occurs as a white amorphous powder.
Betadex Sulfobutyl Ether Sodium salt is an excipient mainly used in nitrogen-containing drugs. It has special affinity and inclusion properties for nitrogen-containing drugs.
Characteristics & Applications:
Betadex Sulfobutyl Ether Sodium Salt is a chemically modified cyclodextrin with a structure designed to optimize the solubility and stability of amount of Betadex Sulfobutyl Ether Sodium Salt that may be used is dependent on the purpose for inclusion in the formulation, the route of administration, and the ability of the cyclodextrin to complex with the drug being delivered.
Pharm Grade Betadex Sulfobutyl Ether Sodium salt is the sulfonated modified sodium salt of beta cyclodextrin,which is an anionic, highly water-soluble cyclodextrin derivative, can be well incorporated with drug molecules to form non-covalent complexes, thereby improving the stability, water solubility and safety of the drug , reducing nephrotoxicity, ease drug hemolysis, control drug release rate, mask bad odor, etc.
Betadex Sulfobutyl Ether Sodium Salt is derived from beta cyclodextrin, which is nephrotoxic when administered parenterally. However, studies have shown that Betadex Sulfobutyl Ether Sodium Salt is well tolerated at high doses, when administered via intravenous bolus injections, orally, and by inhalation. Up to 9 g/day may be administered by IV infusion in a licensed voriconazole formulation. The safety following high doses of Betadex Sulfobutyl Ether Sodium Salt intravenous administration in humans is continually being investigated.
Zhiyuan Betadex Sulfobutyl Ether Sodium Salt has been subjected to an extensive battery of in vitro and in vivo genotoxicity and pharmacological evaluations. No genotoxic or mutagenic changes were observed with Betadex Sulfobutyl Ether Sodium Salt administration. Betadex Sulfobutyl Ether Sodium Salt is biocompatible and exhibits no pharmacological activity. It is rapidly eliminated unmetabolized when administered intravenously.
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Betadex Sulfobutyl Ether Sodium Salt
Description:
Sulfobutylether b-cyclodextrin is an anionic bcyclodextrin derivative with a sodium sulfonate salt separated from the hydrophobic cavity by a butyl spacer group. The substituent is introduced at positions 2, 3, and 6 in at least one of the glucopyranose units in the cyclodextrin structure. Introducing the sulfobutylether (SBE) into b-cyclodextrin can produce materials with different degrees of substitution, theoretically from 1 to 21; the hepta-substituted preparation (SBE7-b-CD) is the cyclodextrin with the most desirable drug carrier properties. Sulfobutylether b-cyclodextrin occurs as a white amorphous powder.
Betadex Sulfobutyl Ether Sodium salt is an excipient mainly used in nitrogen-containing drugs. It has special affinity and inclusion properties for nitrogen-containing drugs.
Characteristics & Applications:
SBE- β –CD is a chemically modified cyclodextrin with a structure designed to optimize the solubility and stability of amount of sulfobutylether β-cyclodextrin that may be used is dependent on the purpose for inclusion in the formulation, the route of administration, and the ability of the cyclodextrin to complex with the drug being delivered.
Betadex Sulfobutyl Ether Sodium salt is the sulfonated modified sodium salt of beta cyclodextrin,which is an anionic, highly water-soluble cyclodextrin derivative, can be well incorporated with drug molecules to form non-covalent complexes, thereby improving the stability, water solubility and safety of the drug , reducing nephrotoxicity, ease drug hemolysis, control drug release rate, mask bad odor, etc.
Zhiyuan Biotechnology ulfobutylether b-cyclodextrin is derived from b-cyclodextrin, which is nephrotoxic when administered parenterally. However, studies have shown that sulfobutylether bcyclodextrin is well tolerated at high doses, when administered via intravenous bolus injections, orally, and by inhalation. Up to 9 g/day may be administered by IV infusion in a licensed voriconazole formulation. The safety following high doses of sulfobutylether β-cyclodextrin intravenous administration in humans is continually being investigated.
Sulfobutylether β-cyclodextrin has been subjected to an extensive battery of in vitro and in vivo genotoxicity and pharmacological evaluations. No genotoxic or mutagenic changes were observed with sulfobutylether β-cyclodextrin administration. High purity Sulfobutylether β-cyclodextrin is biocompatible and exhibits no pharmacological activity. It is rapidly eliminated unmetabolized when administered intravenously.
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Vanillin Inclusion Complex
Zhiyuan Cyclodextrin Complexes Application: it's applied in various kinds of food for a more creamy taste,such as cake, cold drinks, chocolate, candy, and it also can be used for soap, toothpaste, perfume, rubber, plastics, pharmaceuticals.
Product Name: Vanillin inclusion complex
Appearance: white powder
Standard: Enterprise standard
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ITEMS |
Enterprise Standard |
|
Appearance |
white powder, rich milky fragrance |
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Content of Vanillin |
≥ |
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pH |
|
|
Loss on drying |
≤10% |
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Heavy Metal |
≤5ppm |
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The total aerobic microbial count |
≤1000cfu/g |
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The total combined moulds and yeasts count |
≤100cfu/g |
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Escherchia coli |
Absence |
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CAS No 81644-55-5
Description：
Shandong Binzhou Zhiyuan Biotechnology Co.,Ltd is a high-tech enterprise,focusing on cyclodextrin. Sulphur is lively group by oxidation or replace to create higher levels of supramolecular structure.
Quality Cyclodextrin Reagents Characteristics & Applications：
Mercaptoacetic extremely easy adherent to gold surface, thus realize novel applications.
Mercaptoacetic cyclodextrins derivatives extremely suitable for drug induction of anesthesia neuromuscular reversal.
Speciafication:
Please find attached TDS.
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Gamma Cyclodextrin
Description：
Gamma-cyclodextrin is a cydextrin with 8 glucose units connected via α sugar bonds to form a ring structure.
Gamma-cyclodextrin Characteristics & Applications：
Gamma-cyclodextrin has a larger cavity than beta-cyclodextrin, so the cavity can contain a wider range of guest molecules; It has better water solubility,at room temperature 25℃ /100ml, the solubility of gamma-cyclodextrin is , while the solubility of alpha-cyclodextrin is water, and the solubility of beta-cyclodextrin is only water.
Zhiyuan Nature Cyclodextrins Main roles in the food field:
(1) the elimination and cover up of specific odor;
(2) the improvement and improvement of food organization structure;
(3) the reduction and removal of bitter taste;
(4) antioxidant effect;
(5) Maintain and optimize flavor.
Speciafication:
Please find attached TDS.
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